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MOXD1 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| WB, IHC-P, IHC-F, IF, ICC, E |
|---|---|
| Primary Accession | Q6UVY6 |
| Reactivity | Rat, Pig, Dog, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 68 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human MOXD1 |
| Epitope Specificity | 501-600/613 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Endoplasmic reticulum membrane. |
| SIMILARITY | Belongs to the copper type II ascorbate-dependent monooxygenase family. Contains 1 DOMON domain. |
| Post-translational modifications | N-glycosylated. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | MOXD1 is a 613 amino acid single-pass type I membrane protein of the Endoplasmic reticulum that belongs to the copper type II ascorbate-dependent monooxygenase family. Existing as two alternatively spliced isoforms, MOXD1 is expressed in adult spinal cord, adrenal gland, brain, testis, uterus, lung and kidney, as well as fetal liver and brain. MOXD1 is upregulated during replicative senescence in primary fibroblast and umbilical vein endothelial cell cultures, and uses two copper ions per subunit as a cofactor. MOXD1 contains one DOMON domain, undergoes post-translational N-glycosylation and is encoded by a gene that maps to human chromosome 6. Chromosome 6 contains 170 million base pairs, comprises nearly 6% of the human genome and is associated with early onset intestinal cancer, Porphyria cutanea tarda, Parkinson's disease and Stickler syndrome. |
| Gene ID | 26002 |
|---|---|
| Other Names | DBH-like monooxygenase protein 1, 1.14.17.-, Monooxygenase X, MOXD1, MOX |
| Target/Specificity | Highly expressed in lung, kidney, brain and spinal cord. |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | MOXD1 |
|---|---|
| Synonyms | MOX |
| Cellular Location | Endoplasmic reticulum membrane; Single-pass type I membrane protein |
| Tissue Location | Highly expressed in lung, kidney, brain and spinal cord. |
Research Areas
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$ 385.00
Cat# AP56811
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